EFFECTS OF INTERFERONOTHERAPY IN THE TREATMENT OF ATOPIC DERMATITIS WITH ACCOMPANYING SECONDARY IMMUNE INSUFFICIENCY SYNDROME

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Abstract

The low effectiveness of standard basic therapy, the presence of clinical and laboratory signs of secondary immune deficiency in children with atopic dermatitis to determine the need of the appointment of immunocorrective therapy in these patients. It was shown that in children of the younger and older age groups, who used IFN-α drugs together with the standard therapy, the results of the treatment showed better results than in the subgroups that are only on basic therapy.

About the authors

L. P. Sizyakina

Rostov State Medical University

Author for correspondence.
Email: msiziakina@mail.ru

MD, PhD, Head of the Department of Clinical Immunology and Allergology, Director of the Institute of Clinical Immunology,

Rostov 

Russian Federation

E. M. Penechko

Rostov State Medical University

Email: fake@neicon.ru

Post-Graduate Student of the Department of Clinical Immunology and Allergology,

Rostov 

Russian Federation

I. I. Andreeva

Rostov State Medical University

Email: fake@neicon.ru

MD, PhD, Professor of the Department of Clinical Immunology and Allergology,

Rostov 

Russian Federation

References

  1. McClean M., Silverberg J. I. Statistical reporting in randomized controlled trials from the dermatology literature: a review of 44 dermatology journals. British Journal of Dermatology. 2015, 173; 1, 172–183.
  2. Лусс Л.В., Михеева Г. Н., Тузлукова Е. Б. Синдром вторичной иммунной недостаточности у больных с аллергическими заболеваниями и методы ее коррекции // Лечащий врач. – 2013. – № 6. – С. 19–20.
  3. Пенечко Е.М., Сизякина Л. П. Эффективность заместительной терапии препаратом интерферонаальфа в лечении атопического дерматита у детей с сопутствующим синдромом вторичной иммунной недостаточности // Цитокины и воспаление. – 2010. – Т. 9, № 4. ‒ С. 109–110.

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Copyright (c) 2019 Sizyakina L.P., Penechko E.M., Andreeva I.I.

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