INFLUENCE OF MILIACIN TRITERPENOID ON ANTILYSOCIMATIC ACTIVITY OF MICROORGANISMS

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Abstract

The inhibitory effect of triterpenoid miliacin in a dose of 50 μg / ml on the persistent trait of microorganisms – antilysocyme activity was established. The revealed property of militia along with its immunomodulating activity can provide a previously identified protective effect in experimental Salmonella infection.

About the authors

Y. V. Filippova

Orenburg State Medical University, Ministry of Health of the Russian Federation

Author for correspondence.
Email: probllab.orenburg@mail.ru

Ph.D., Researcher, Problem Research Laboratory,

Orenburg

Russian Federation

T. A. Bondarenko

FGBUN Institute for Cellular and Intracellular Symbiosis

Email: fake@neicon.ru

Researcher, Laboratory of Biomonitoring and Molecular Genetic Research,

Orenburg

Russian Federation

T. V. Panfilova

Orenburg State Medical University, Ministry of Health of the Russian Federation

Email: fake@neicon.ru

PhD, Associate Professor, Department of Pathological Physiology,

Orenburg

Russian Federation

A. D. Zheleznova

Orenburg State Medical University, Ministry of Health of the Russian Federation

Email: fake@neicon.ru

PhD, Associate Professor, Department of Pathological Physiology,

Orenburg

Russian Federation

Y. A. Sarycheva

Orenburg State Medical University, Ministry of Health of the Russian Federation

Email: fake@neicon.ru

PhD, Associate Professor, Department of Pathological Physiology,

Orenburg

Russian Federation

A. A. Tokareva

Orenburg State Medical University, Ministry of Health of the Russian Federation

Email: fake@neicon.ru

Assistant of the Department of Pathological Physiology,

Orenburg

Russian Federation

References

  1. Бухарин О. В. Персистенция патогенных бактерий. М.: Медицина, 1999, 322.
  2. Фролов Б. А., Железнова А. Д., Чайникова И. Н., Панфилова Т. В., Медведева И. П., Филиппова Ю. В., Смолягин. А. И. Защитный эффект милиацина при экспериментальной сальмонеллезной инфекции. Журн. Микробиол. 2013, 6, 3–8.

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Copyright (c) 2019 Filippova Y.V., Bondarenko T.A., Panfilova T.V., Zheleznova A.D., Sarycheva Y.A., Tokareva A.A.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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