ENDOTELIOPROTECTIVE EFFECT OF INTRAVENOUS IMMUNOGLOBULINS IN OBSTETRIC PATHOLOGY. METHODOLOGICAL APPROACHES

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Abstract

Intravenous immunoglobulins are investigated as cytoprotectors that can eff ectively protect endothelial cells from diff erent cytopathic factors contained in blood serum. We developed a method to evaluate the endothelioprotective eff ect of intravenous immunoglobulins.

About the authors

S. V. Chepanov

Тhe Federal State Budgetary Scientific Institution “The Research Institute of Obstetrics, Gynecology and Reproductology named after D. O. Ott”

Author for correspondence.
Email: chepanovsv@gmail.com

MD, Head of the laboratory of immunology,

Saint Petersburg

Russian Federation

T. N. Shlachtenko

The Center for Diagnosis, Prevention and Treatment of Miscarriage at Maternity Hospital № 1

Email: fake@neicon.ru

MD, immunologist,

Saint Petersburg

Russian Federation

E. A. Kornyushina

Тhe Federal State Budgetary Scientific Institution “The Research Institute of Obstetrics, Gynecology and Reproductology named after D. O. Ott”

Email: fake@neicon.ru

MD, obstetrician-gynecologist of the Obstetric Department of Pregnancy Pathology, Senior Researcher,

Saint Petersburg

Russian Federation

K. N. Chudotvorov

The Pavlov First Saint Petersburg State Medical University

Email: fake@neicon.ru

student,

Saint Petersburg

Russian Federation

E. S. Orlova

Тhe Federal State Budgetary Scientific Institution “The Research Institute of Obstetrics, Gynecology and Reproductology named after D. O. Ott”

Email: fake@neicon.ru

postgraduate student,

Saint Petersburg

Russian Federation

S. A. Selkov

Тhe Federal State Budgetary Scientific Institution “The Research Institute of Obstetrics, Gynecology and Reproductology named after D. O. Ott”

Email: fake@neicon.ru

Doctor of Medical Sciences, Professor, Head of the Department of Immunology and Intercellular Interactions,

Saint Petersburg

Russian Federation

References

  1. Макацария А. Д., Бицадзе В. О., Хизроева Д. Х., Макацария Н. А. Патогенетическое значение антифосфолипидных антител // Практическая медицина. –2012. – Т. 5. – № 60. – С. 9–21.
  2. Шляхтенко Т. Н., Алябьева Е. А., Аржанова О. Н., Сельков С. А. Антифосфолипидный синдром при невынашивании беременности // Журнал акушерства и женских болезней. – 2015. – Т. 54. – № 5. – С. 69–76.
  3. Сельков С. А., Соколов Д. И., Чепанов С. В. Иммунорегуляторные эффекты иммуноглобулинов для внутривенного введения // Медицинская иммунология. –2013. – Т. 15. – № 1. – С. 5–12.

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Copyright (c) 2019 Chepanov S.V., Shlachtenko T.N., Kornyushina E.A., Chudotvorov K.N., Orlova E.S., Selkov S.A.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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