Email this article CONDITION OF INDICATORS OF INTERACTION OF THE INTER-CELLULAR MATRIX IN MEN WITH CHRONIC CHLAMYDIAL URETHRITIS BEFORE AND AFTER THE TREATMENT
- Authors: Chepurnova N.S.1, Kostyushko A.V.1, Tulupova M.S.2
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Affiliations:
- “Pacific State Medical University”, Ministry of Health of the Russian Federation
- “Peoples’ Friendship University of Russia” Ministry of Education and Science of the Russian Federation
- Issue: Vol 22, No 2-1 (2019)
- Pages: 635-637
- Section: ORIGINAL ARTICLES
- URL: https://rusimmun.ru/jour/article/view/245
- DOI: https://doi.org/10.31857/S102872210006998-2
- ID: 245
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Abstract
The data on the level of matrix metalloproteinase-9 and its tissue inhibitors of the 1st and 2nd types in the serum of venous blood in men with chronic chlamydial urethritis before and after treatment are presented. An increase in the level of MMP-9 against the background of normal values of TIMP-1 and low levels of TIMP-2 indicates the destructive potential of the infectious process. An increase in the effectiveness of combination therapy using recombinant interferon-gamma has been observed.
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About the authors
N. S. Chepurnova
“Pacific State Medical University”, Ministry of Health of the Russian Federation
Author for correspondence.
Email: dr.cns@yandex.ru
PhD, Assistant, Department of Normal and Pathological Physiology,
Vladivostok
Russian FederationA. V. Kostyushko
“Pacific State Medical University”, Ministry of Health of the Russian Federation
Email: fake@neicon.ru
PhD, Associate Professor, Department of Normal and Pathological Physiology,
Vladivostok
Russian FederationM. S. Tulupova
“Peoples’ Friendship University of Russia” Ministry of Education and Science of the Russian Federation
Email: fake@neicon.ru
Ph.D., doctoral candidate of the Department of Obstetrics and Gynecology with a course of perinatology,
Vladivostok
Russian FederationReferences
- Маркелова Е. В., Здор В. В., Романчук А. Л., Бирко О. Н. Матриксные металлопротеиназы: их взаимосвязь с системой цитокинов, диагностический и прогностический потенциал. // Иммунопатология, аллергология, инфектология. 2016, 2. 11–22.
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