IMMUNE DISORDERS AND ARTERIAL PRESSURE PATIENTS WITH ARTERIAL HYPERTENSION

E. V. Gavrilyuk; Гаврилюк Е. В.; A. I. Konoplya; Конопля А. И.; V. P. Mikhin; Михин В. П.; Y. V. Prokofieva; Прокофьева Ю. В.; L. N. Serikova; Серикова Л. Н.

doi:10.31857/S102872210006719-5

IMMUNE DISORDERS AND ARTERIAL PRESSURE PATIENTS WITH ARTERIAL HYPERTENSION

Authors: Gavrilyuk E.V.¹, Konoplya A.I.¹, Mikhin V.P.¹, Prokofieva Y.V.¹, Serikova L.N.¹
Affiliations:
1. Kursk State Medical University
Issue: Vol 22, No 2-2 (2019)
Pages: 736-738
Section: ORIGINAL ARTICLES
URL: https://rusimmun.ru/jour/article/view/284
DOI: https://doi.org/10.31857/S102872210006719-5
ID: 284

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Abstract

The study included 68 patients with arterial hypertension 1, 2 and 3 degrees, in whom the concentration of cytokines and components of the complement system was determined in the blood plasma before and after 4 weeks of systemic antihypertensive therapy. In patients with arterial hypertension prior to the onset of systemic antihypertensive therapy, changes in the level of pro-inflammatory and antiinflammatory cytokines and activation of the complement system were found in proportion to the level of blood pressure. In patients with arterial hypertension who have reached the target values of blood pressure against the background of ongoing pharmacotherapy, the severity of immune changes is significantly lower than in patients whose blood pressure has not reached the target level.