PREVALENCE OF ANTINUCLEAR ANTIBODIES IN HEALTHY CHILDREN AND ADULTS

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Abstract

Healthy donors (n=100) of 21–59 years old and healthy children (n=55) of 2–17 years old were examined. Antinuclear antibodies were determined by indirect immunofluorescence assay. It was found that 7 adults (7%) and 10 children (18%) had diagnostic titers of antinuclear antibodies detected by indirect immunofluorescence assay. In healthy children and adults homogeneous and speckled fluorescence patterns were observed more often.

About the authors

I. M. Krivolapova

Regional Child’s Clinical Hospital № 1;
Institute of Immunology and Physiology Ural Branch of the Russian Academy of Sciences

Author for correspondence.
Email: krivolapovaim@mis66.ru

Biologist, Clinical Diagnostic Laboratory;

Junior Research Associate, Laboratory of Immunology of Inflammation, 

Yekaterinburg

Russian Federation

I. A. Pashnina

Regional Child’s Clinical Hospital № 1;
Institute of Immunology and Physiology Ural Branch of the Russian Academy of Sciences

Email: fake@neicon.ru

PhD, Head of the laboratory, Clinical and diagnostic laboratory;

Senior Research Associate, Laboratory of Immunology of Inflammation,

Yekaterinburg

Russian Federation

V. A. Chereshnev

Institute of Immunology and Physiology Ural Branch of the Russian Academy of Sciences

Email: fake@neicon.ru

PhD, Professor, Full Member, Russian Academy of Sciences, Main Research Associate, 

Yekaterinburg

Russian Federation

References

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  2. Cacciapaglia F., Arcarese L., Rigon A., Vadacca M., Valorani M. G., Pozzilli P., Afeltra A. Antinuclear antibodies prevalence in Filipinos migrated to Italy. Eur. Rev. Med. Pharmacol. Sci. 2008, 12; 4, 267–270.
  3. Wananukul S., Voramethkul W., Kaewopas Y., Orrawadee H. Prevalence of positive antinuclear antibodies in healthy children. Asian pacific journal of allergy and immunology. 2005, 23, 153–157.
  4. Allen R.C., Dewez P., Stuart L. Gatenby P. A., Sturgess A. Antinuclear antibodies using HEp-2 cells in normal children and in children with common infections. J. Paediatr. Child. Health. 1991, 27; 1, 39–42.
  5. Пашнина, И.А, Плотникова И. А., Криволапова И. М., Цегельная В. П., Тузанкина И. А., Каракина М. Л., Семишева И. А. Признаки иммунопатологических процессов у детей, проживающих на территории с высокой техногенной нагрузкой. Известия Самарского научного центра Российской академии наук. 2013, 15; 3(6), 1904–1907.

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Copyright (c) 2019 Krivolapova I.M., Pashnina I.A., Chereshnev V.A.

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