CYTOKINES IN THE PATHOGENESIS OF SPONTANEOUS URTICARIA

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Abstract

IL-4 and TNFα cytokines are involved in the pathogenesis of spontaneous urticaria and can be considered as potential biomarkers of the disease.

About the authors

A. E. Krivonkina

State Budget Institution of Health Care of the Republic of Karelia “Emergency Hospital”

Author for correspondence.
Email: Krivonkina@yandex.ru

allergist-immunologist,

Petrozavodsk

Russian Federation

S. M. Yudina

Federal State Budget Educational Institution of Higher Education “Kursk State Medical University”

Email: fake@neicon.ru

doctor of medical sciences, professor, Head of the Department of Clinical Immunology, Allergology and Phthisiopulmonology

Petrozavodsk

Russian Federation

A. M. Bahirev

Federal State Budget Educational Institution of Higher Education “Petrozavodsk State University” Medical Institute

Email: fake@neicon.ru

PhD, docent, Department of Faculty Therapy, Phthisiology, Infectious Diseases and Epidemiology,

Petrozavodsk

Russian Federation

References

  1. Papatya Bayrak Degirmenci, Cengiz Kırmaz, Seda Vatansever, Ece Onur, Emine Nal, Soner Erdin, Beyhan Ozyurt. Analysis of the association of chronicspontaneousurticaria with interlekin-4, -10, transforming growth factor-β1, interferon-γ, interleukin-17A and -23 by autologous serum skin test. Postepy Dermatologii I Alergologii. 2017, 34(1), 70–76.
  2. Баранова Н. И., Ащина Л. А., Орлова Е. А. Цитокиновый профиль и показатели Т-клеток у больных аутоиммунной формой хронической крапивницы. Иммунопатология, аллергология, инфектология. 2012, 4, 61–65.
  3. Atwa M. A., Emara A. S., Youssef N., Bayoumy N. M. Serum concentration of IL-17, IL-23 and TNF-α among patients with chronic spontaneous urticaria: association with disease activity and autologous serum skin test. J Eur Acad Dermatol Venereol. 2014, 28(4), 469–74.
  4. Kolkhir P., André F., Church M. K., Maurer M., Metz M. Potential blood biomarkers in chronic spontaneous urticaria. Clin Exp Allergy. 2017, 47(1), 19–36.

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Copyright (c) 2019 Krivonkina A.E., Yudina S.M., Bahirev A.M.

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