IMMUNORABILITATION IN CHRONIC ISCHEMIA OF THE BRAIN

We examined 26 patients of the neurological department of the BMU “Kursk Regional Clinical Hospital” with chronic cerebral ischemia stage II against the background of hypertensive disease stage II. All were divided equally by random randomization and within two weeks received a comprehensive basic pharmacological therapy (enalapril, vinpocetine, ceraxon and mexicor). Half of the patients additionally received polyoxidonium. Immune disorders were assessed by indicators in the peripheral blood of the functional metabolic activity of neutrophils, plasma levels of cytokines, complement components and their inhibitors. Prior to treatment, violations indicating the presence of immune infl ammation were identifi ed. Inclusion of polyoxidonium into the complex pharmacotherapy eff ectively corrects the altered immune status parameters.