THE LEVEL OF PROINFLAMMATORY CYTOKINES IN PATIENTS WITH POSTOPERATIVE HYPOTHYRHYOSIS COMPLICATED BY HYDROPERICARD

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Abstract

In 46 women out of 136 (mean age 48.0 ± 2.3 years) who were operated on for a nodular goiter, a pericardial effusion and elevated serum levels of IL-6 and TNF-α were detected before the operation. After the operation, as the volume of hydropericardium increased, an increase in the serum cytokine content was observed with a direct correlation (r = 0.39; р<0.05) between TNF-α and the volume of effusion in the pericardial cavity.

About the authors

I. I. Rybchinskaya

Departmental Clinical Hospital at st. Orenburg Russian Railways

Author for correspondence.
Email: fake@neicon.ru

Candidate of Medical Sciences, deputy chief for polyclinic work,

Orenburg

Russian Federation

K. M. Ivanov

Orenburg State Medical University

Email: fake@neicon.ru

Doctor of Medicine, Professor, Head of the department of propedeutics of internal diseases,

Orenburg

Russian Federation

E. V. Ermolina

Orenburg State Medical University

Email: fake@neicon.ru

Candidate of Biological Sciences, senior researcher of the problem research laboratory,

Orenburg

Russian Federation

N. G. Shkatova

Orenburg State Medical University

Email: natasha_shkatova@mail.ru

Assistant of the Department of Internal Medicine Propaedeutics,

Orenburg

Russian Federation

References

  1. Будневский А. В., Бурлачук В. Т., Грекова Т. И. Гипотиреоз и сердечно-сосудистая патология. Клиническая тиреодология. 2004, 2(2),7–14.
  2. Дранник Г. Н. Клиническая иммунология и аллергология. М.: ООО «Медицинское информационное агентство». 2003, 604.
  3. Палеев Н. П., Палеев Ф. Н. Цитокины и их роль в патогенезе заболеваний сердца. Клиническая медицина. 2004, 5, 4–7.
  4. Петунина Н. А. Сердечно-сосудистые осложнения гипотиреоза. // Врач. 2007, 4, 2–5.

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Copyright (c) 2019 Rybchinskaya I.I., Ivanov K.M., Ermolina E.V., Shkatova N.G.

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