CONDITION OF JAK-STAT SYSTEM IN PURULENT-INFLAMMATORY DISEASES OF SOFT TISSUES

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Abstract

Characterization of impaired JAK-STAT-signal transduction and SOCS regulation in cytokine-dependent activation in purulent-inflammatory diseases of soft tissues.

About the authors

I. A. Snimschikova

Oryol State University named after I. S. Turgenev

Author for correspondence.
Email: fake@neicon.ru

Professor, doctor of medicine, head of Department of Immunology and specialized clinical disciplines,

Oryol 

Russian Federation

N. A. Khabina

Oryol State University named after I. S. Turgenev

Email: fake@neicon.ru

Associate Professor at the Department of pharmacology, clinical pharmacology and pharmacy,

Oryol 

Russian Federation

M. O. Plotnikova

Oryol State University named after I. S. Turgenev

Email: revyakina_masha@mail.ru

Associate Professor at the Department of Immunology and specialized clinical disciplines,

Oryol 

Russian Federation

I. A. Afonina

Oryol State University named after I. S. Turgenev

Email: fake@neicon.ru

Associate Professor at the Department of Immunology and specialized clinical disciplines,

Oryol 

Russian Federation

A. D. Chestnihina

Oryol State University named after I. S. Turgenev

Email: fake@neicon.ru

Associate Professor at the Department of Public health, health and hygiene,

Oryol 

Russian Federation

References

  1. Aboulhoda B. E. Age-related remodeling of the JAK/ STAT/SOCS signaling pathway and associated myocardial changes: From histological to molecular level/ Ann Anat. 2017 Nov; 214:21–30.
  2. Almeida-Oliveira A. R., Aquino-Junior J., Abbasi A., Santos-Dias A., Oliveira-Junior M. C., Alberca-Custodio R. W., Rigonato-Oliveira N. C., Salles-Dias L. P., Damaceno-Rodrigues N. R., Caldini E. G., Arantes-Costa F. M., Ligeiro-Oliveira A. P., Belvisi M. G., Vieira R. P. Effects of aerobic exercise on molecular aspects of asthma: involvement of SOCS-JAK-STAT/ ExercImmunol Rev.2019; 25:50–62.
  3. Feng Y., Sanders A.J., Morgan L.D., Owen S. Ruge F., Harding K. G., Jiang W. G. Expression of the SOCS family in human chronic wound tissues: Potential implications for SOCS in chronic wound healing / Int J Mol Med.2016 Nov; 38 (5)2016.
  4. Шохина М. Д., Снимщикова И. А., Халилов М. А., Честнихина А. Д., Афонина И. А., Кабина Н. А. Динамика изменений концентрации метаболитов оксида азота при раневой инфекции /Медицинская иммунология. 2017. Т. 19. № S. С. 336.

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Copyright (c) 2019 Snimschikova I.A., Khabina N.A., Plotnikova M.O., Afonina I.A., Chestnihina A.D.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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