RELATIONSHIP OF IMMUNE AND METABOLIC DISORDERS IN CHRONIC ISCHEMIA OF THE BRAIN

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Abstract

The study included 104 patients hospitalized in the neurological department of the Kursk Regional Clinical Hospital with chronic cerebral ischemia (CCI) against the background of hypertension of the II stage, equally divided by the I and II stages of the disease. In the blood (plasma, neutrophils and erythrocytes), the parameters of the immune and metabolic status were determined with an assessment of the relationship between the studied parameters. In patients with CCI stage I and stage II it is established that there are more reliable interrelations in patients with early stage of the disease compared with those in patients with stage II, and this probably indicates a greater disadaptation of the mechanisms for maintaining immune and metabolic homeostasis in patients with CCI stage II, compared with patients with stage I disease.

About the authors

A. A. Shulginova

Kursk State Medical University

Author for correspondence.
Email: snaky292@yandex.ru

Ph.D., Assistant of the Department of Neurology and Neurosurgery,

Kursk

Russian Federation

G. N. Ryzhikova

Kursk State Medical University

Email: fake@neicon.ru

Ph.D., Senior Lecturer, Department of Biological Chemistry,

Kursk

Russian Federation

I. I. Colomoets

Kursk State Medical University

Email: fake@neicon.ru

Ph.D., Assistant of the Department of Biological Chemistry,

Kursk

Russian Federation

V. A. Ragulina

Kursk State Medical University

Email: fake@neicon.ru

PdH, assistant of professor «Kursk State Medical University»,

Kursk

Russian Federation

References

  1. Гусев Е. И., Чуканова А. С. Современные патогенетические аспекты формирования хронической ишемии мозга. Журнал неврологии и психиатрии, 2015, 3, 4–8.
  2. Гаврилюк Е. В., Конопля А. И., Караулов А. В. Роль иммунных нарушений в патогенезе артериальной гипертонии. Иммунология, 2016, 37 (1), 29–34.
  3. Земской А. М. Клиническая иммунология и аллергология. Воронеж 2016, 288.
  4. Конопля А. И., Шатохин М. Н., Маврин М. Ю., Гаврилюк В. П. Взаимосвязь иммунных и оксидантных нарушений при остром обструктивном и необструктивном пиелонефрите. Клиническая медицина, 2017, 95 (4), 362–368.

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Copyright (c) 2019 Shulginova A.A., Ryzhikova G.N., Colomoets I.I., Ragulina V.A.

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