Email this article CROSS-LINKING ALLERGY IN BRONCHIAL ASTMA AND ALLERGEN-ASSOCIATED MOLECULAR PATTERNS (AAMP)
- Authors: Klimov V.V.1, Sviridova V.S.1, Isaev P.Y.1, Koshovkina T.V.1
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Affiliations:
- Siberian State Medical University
- Issue: Vol 20, No 2 (2017)
- Pages: 146-147
- Section: Articles
- URL: https://rusimmun.ru/jour/article/view/607
- ID: 607
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Abstract
To evaluate content of IL-4 in lymphoblast transformation test (LTT) supernatants of 15 persons with asthma, 16 patients with asthma in association with allergy to prawns and 15 healthy persons were studied. All sufferers of asthma were sensibilisized to Der p 1 (Dermatophagoides pteronissinus). There have not been revealed any differences between the IL-4 in different groups that may be indirectly propose the presence of Allergen-Associated Molecular Patterns (AAMPs) in patients, which might smooth out received results.
About the authors
V. V. Klimov
Siberian State Medical University
Author for correspondence.
Email: noemail@neicon.ru
Russian Federation
V. S. Sviridova
Siberian State Medical University
Email: noemail@neicon.ru
Russian Federation
P. Yu. Isaev
Siberian State Medical University
Email: noemail@neicon.ru
Russian Federation
T. V. Koshovkina
Siberian State Medical University
Email: noemail@neicon.ru
Russian Federation
References
- Pali-Scholl I., Jensen-Jarolim E. The concept of allergen-associated molecular patterns (AAMP). Current Opinion in Immunology. 2016, 42,113-118.
- Treanor B. B-cell receptor: from resting state to activate. Immunology. 2012, 136:21-27.
- Deak P. E., Vrabel M. R., Pizzuti V. J., et al. Nanoallergens: A multivalent platform for studying and evaluating potency of allergen epitopes in cellular degranulation. Exp Biol Med (Maywood). 2016, 241,996-1006.
- Шкатова А. Н. Динамика содержания ИЛ-4 у больных микогенными респираторными ал-лергозами при проведение специфической иммунотерапии. Вестник СГМУ (Томск) 2000, 1, 2, 93-94.
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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).