Email this article HUMORAL IMMUNOLOGICAL PARAMETERS IN CHILDREN WITH JUVENILE IDIOPATHIC ARTHRITIS AND REACTIVE ARTHRITIS
- Authors: Pashnina I.A.1,2, Krivolapova I.M.1,2, Chereshnev V.A.2
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Affiliations:
- Regional Children's Clinical Hospital № 1
- Institute of Immunology and Physiology, Urals Branch of the Russian Acad. Sci.
- Issue: Vol 20, No 2 (2017)
- Pages: 194-197
- Section: Articles
- URL: https://rusimmun.ru/jour/article/view/623
- ID: 623
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Abstract
The levels of humoral immunological parameters in children of 2-17 years old with oligoarticular juvenile idiopathic arthritis (n = 98), with reactive arthritis (n = 26) and conditionally healthy children (n = 42) were examined. There were no differences in the concentration of C-reactive protein and antibodies to modified citrullinated vimentin between healthy children and patients with joint diseases. The level of antibodies to extractable nuclear antigens and the antinuclear factor titer in children with juvenile arthritis were higher, than in healthy children and patients with reactive arthritis. The frequency of antibodies to extractable nuclear antigens and modified citrullinated vimentin in children with juvenile arthritis and reactive arthritis was low, most often an antinuclear factor in these patients was detected.
About the authors
I. A. Pashnina
Regional Children's Clinical Hospital № 1; Institute of Immunology and Physiology, Urals Branch of the Russian Acad. Sci.
Author for correspondence.
Email: noemail@neicon.ru
Russian Federation
I. M. Krivolapova
Regional Children's Clinical Hospital № 1; Institute of Immunology and Physiology, Urals Branch of the Russian Acad. Sci.
Email: noemail@neicon.ru
Russian Federation
V. A. Chereshnev
Institute of Immunology and Physiology, Urals Branch of the Russian Acad. Sci.
Email: noemail@neicon.ru
Russian Federation
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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).