CHARACTERISTICS OF SYSTEMIC IMMUNITY IN WOMEN WITH ENDOMETRIOSIS AND GENITAL INFECTION

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Abstract

The study of the indices of systemic immunity in women with endometriosis, depending on the presence or absence of pathogens of genital infection. Pathogens of genital infection were found in 50 % of women with endometriosis in endocervix, endometrium, peritoneal fluid and in the foci of endometriosis. The most commonly identified were Ureaplasma spp, HPV and CMV. Changes in the indices of systemic immunity in women with endometriosis in comparison with the control group were more pronounced in the presence of pathogens of genital infection.

About the authors

L. F. Zaynetdinova

FSBEI HE SUSMU MOH

Author for correspondence.
Email: noemail@neicon.ru
Russian Federation

L. F. Telesheva

FSBEI HE SUSMU MOH

Email: noemail@neicon.ru
Russian Federation

A. V. Koryaushkina

FSBEI HE SUSMU MOH

Email: noemail@neicon.ru
Russian Federation

References

  1. Телешева, Л.Ф., Долгушина В. Ф., Зябкина А. Ю., Фортыгин А. Я., Долгушин И. И. Функциональная активность фагоцитирующих клеток репродуктивного тракта женщин при воспалении верхнего отдела гениталий. Журнал микробиологии, эпидемиологии и иммунобиологии 2001, 4, 104-107.
  2. Agic А., Djalali S., Diedrich K., Hornung D. Apoptosis in endometriosis. Gynecol. Obstet. Invest. 2009, Vol. 68, N 4, 217-223.
  3. Matarese G., De Placido G., Nicas Y., Alviggi C. Patogenesis of endometriosis: natura limmunity disfunction or autoimmune disease. Trends Mol. Med. 2003, Vol. 9, № 5, 223-228.
  4. Kobayashi H., Higashiura Y., Shigetomi H., Kajihara H. Pathogenesis of endometriosis: The role of initial infection and subsequent sterile inflammation (Review) Mol. Med. Rep. 2014, 9(1), 9-15.

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Copyright (c) 2017 Zaynetdinova L.F., Telesheva L.F., Koryaushkina A.V.

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