FEATURES OF DIFFERENTIATION OF DENDRITIC CELLS IN TYMUS IN CHILDREN DEPENDING ON TYPE OF CYANOSIS IN CONGENITAL HEART DISEASES

N. P. Loginova; Логинова Н. П.; E. G. Orlova; Орлова Е. Г.; S. V. Shirshev; Ширшев С. В.; O. A. Loginova; Логинова О. А.; R. M. Shekhmametyev; Шахмаметьев Р. М.

FEATURES OF DIFFERENTIATION OF DENDRITIC CELLS IN TYMUS IN CHILDREN DEPENDING ON TYPE OF CYANOSIS IN CONGENITAL HEART DISEASES

Authors: Loginova N.P.¹, Orlova E.G.², Shirshev S.V.², Loginova O.A.¹, Shekhmametyev R.M.³
Affiliations:
1. Perm State Medical University named after Academician E. A. Wagner
2. Institute of Ecology and Genetics of Microorganisms
3. Federal Center for Cardiovascular Surgery named after S. G. Sukhanov
Issue: Vol 20, No 3 (2017)
Pages: 413-415
Section: Articles
URL: https://rusimmun.ru/jour/article/view/707
ID: 707

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Abstract

The specific features of differentiation of dendritic cells (DC) of the thymus in children with depending on the type of cyanosis at congenital heart diseases (CHD) have been studied. It has been established that the accumulation of DC in the medullar and cortical compartment of the thymus occurs at CHD, especially in the case of blue types of CHD. When comparing the blue and white types of CHD, a change in the content of myeloid and plasmacytoid DC of the thymus was revealed. Thus, hypoxia affects the differentiation of the DC at thymus at CHD.

Keywords

дендритные клетки тимуса, врожденные пороки сердца, цианоз, дети, dendritic cells of thymus, congenital heart diseases, cyanosis, children

References

Дударев И. В. Иммунологическая и гемодинамическая характеристика детей с врожденными пороками сердца синего и бледного типа. Иммунология. 2002, 3, 167-170.
Wu L., Shortman K. Heterogeneity of thymic dendritic cells. Semin. Immunol. 2005, 17, 304-312.
Логинова Н. П. Особенности экспрессии FOXP3 и RORyt СD4+-тимоцитами у детей в зависимости от сложности врожденных пороков сердца. Биологические мембраны. 2016. Т. 33, № 1. С. 98-104.

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FEATURES OF DIFFERENTIATION OF DENDRITIC CELLS IN TYMUS IN CHILDREN DEPENDING ON TYPE OF CYANOSIS IN CONGENITAL HEART DISEASES

Full Text

Abstract

Keywords

About the authors

N. P. Loginova

E. G. Orlova

S. V. Shirshev

O. A. Loginova

R. M. Shekhmametyev

References

Supplementary files

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