HUMAN PAPILLOMAVIRUS INFECTION: А CYTOKINE IMBALANCE IN WOMEN AND MEN FROM COUPLES

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Abstract

The study presents the results of the study of the most significant cytokines of cervical mucus in women and the ejaculate of 38 married couples with a papillomavirus infection. Changes in the levels of indicators are as one-sided, expressed in an increase in the number of IL-2, IL-10, sIgA, and versatile, characterized by a decrease in IFN-γ in women, with its normal level in men.

About the authors

O. V. Lysenko

South Ural state medical University

Author for correspondence.
Email: noemail@neicon.ru
Russian Federation

D. A. Markeeva

South Ural state medical University

Email: noemail@neicon.ru
Russian Federation

O. I. Letyaeva

South Ural state medical University

Email: noemail@neicon.ru
Russian Federation

D. S. Prokop'ev

South Ural state medical University

Email: noemail@neicon.ru
Russian Federation

References

  1. Moreira E. D. Jr., Giuliano A. R., Palefsky J., et al. Incidence, clearance, and disease progression of genital human papillomavirus infection in heterosexual men // J Infect Dis.- 2014.- 210(2).- Р. 192-9.
  2. Behbahani H., Walther-Jallow L., Klareskog E. et al. Proinflammatory and type1cytolineexpression in cervical mucosa during HlV-1 and human Papillomavirus infection// J. Acquir Immune Defic Syn-dr.-2007.- May.- V.1.- 45 (1).- с. 9-19.
  3. Зиганшин О. Р., Летяева О. И., Телешева Л. Ф., Абрамовских О. С. Иммунологические методы исследования в диагностике папилломавирус-ной инфекции// Вестник последипломного медицинского образования. 2014, № 4. С. 78-79.
  4. Audirac-Chalifour A., Torres-Poveda K., Bahena-Roman M., et al. Cervical Microbiome and Cytokine Profile at Various Stages of Cervical Cancer: A Pilot Study. PLoS One. 2016 Apr 26;11(4): e0153274.
  5. Лысенко О. В., Телешева Л. Ф., Троянова А. В. Папилломавирусная инфекция у семейных пар: заметки к теме. Современные проблемы дерматовенерологии, иммунологии и врачебной косметологии. 2013, 8; 3 (26), 49-55.

Copyright (c) 2017 Lysenko O.V., Markeeva D.A., Letyaeva O.I., Prokop'ev D.S.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Свидетельство о регистрации СМИ ПИ № 77 - 11525 от 04.01.2002 выдано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).


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