MEASLES DIAGNOSTICS: PROBLEMS AND MODERN APPROACHES

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Abstract

Key methods of measles diagnostics are presented in the paper. Immunoenzyme, chemiluminiscent assays and polymerase chain reaction are the most effective modern measles diagnostic methods. Development of more perfect diagnostic techniques is essential component of WHO Global measles and rubella strategic plan.

About the authors

M. B. Rayev

FSBSI Institute of Ecology and Genetics of Microorganisms UB RAS

Author for correspondence.
Email: noemail@neicon.ru
Russian Federation

P. V. Khramtsov

FSBSI Institute of Ecology and Genetics of Microorganisms UB RAS; FSBEIHPE Perm State National Research University

Email: noemail@neicon.ru
Russian Federation

M. S. Bochkova

FSBSI Institute of Ecology and Genetics of Microorganisms UB RAS

Email: noemail@neicon.ru
Russian Federation

V. P. Timganova

FSBSI Institute of Ecology and Genetics of Microorganisms UB RAS

Email: noemail@neicon.ru
Russian Federation

S. A. Zamorina

FSBSI Institute of Ecology and Genetics of Microorganisms UB RAS; FSBEIHPE Perm State National Research University

Email: noemail@neicon.ru
Russian Federation

References

  1. Bester J. C. Measles and Measles Vaccination: A Review. jAMA Pediatrics. 2016, 170 (vol.), 1209-1215.
  2. Vero/hSLAM Cells for Isolation of Measles Virus. https://www.cdc.gov/measles/lab-tools/vero-slam. html
  3. De Ory F., Minguito T., Balfagon P., Sanz J. C. Comparison of chemiluminescent immunoassay andEL-ISA for measles IgG and IgM. APMIS. 2015, 123 (vol.), 648-651.
  4. Yasui Y., Mori Y., Adachi H., Kobayashi S., Yamashi-ta T., Minagawa H. Detection and genotyping of rubella virus from exanthematous patients suspected of having measles using reverse transcription-PCR. Jpn. J. Infect. Dis. 2014, 67 (vol.), 389-391.
  5. Holzmann H., Hengel H., Tenbusch M., Doerr H. W. Eradication of measles: remaining challenges. Med. Microbiol. Immunol. 2016, 205 (vol.), 201-208.

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Copyright (c) 2017 Rayev M.B., Khramtsov P.V., Bochkova M.S., Timganova V.P., Zamorina S.A.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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