Email this article INTRASPECIFIC AND INTERSPECIFIC PATTERNS OF MICROBIOTA - INFLAMMATORY HOST POTENTIAL INTERACTIONS IN CHILDREN WITH ASD
- Authors: Timofeeva A.V.1, Filippova Y.Y.1, Polyakova E.A.1, Burmistrova A.L.1
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Affiliations:
- Chelyabinsk State University
- Issue: Vol 20, No 3 (2017)
- Pages: 529-531
- Section: Articles
- URL: https://rusimmun.ru/jour/article/view/755
- ID: 755
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Abstract
Analysis of correlation links of intraspecies patterns - “microbe - microbe”, “microbe - endotoxin”, inflammatory potential of the host “cytokine - cytokine” and interspecies - “microbe - host” demonstrates close relationships between members of the small intestine microbiota community in healthy children and in children with ASD. Statistically significant correlations of the pattern of the inflammatory potential of the cytokine-cytokine host and of the pattern of interspecies links “microbe - host” were registered only in the group of children with ASD.
About the authors
A. V. Timofeeva
Chelyabinsk State University
Author for correspondence.
Email: noemail@neicon.ru
Russian Federation
Yu. Yu. Filippova
Chelyabinsk State University
Email: noemail@neicon.ru
Russian Federation
E. A. Polyakova
Chelyabinsk State University
Email: noemail@neicon.ru
Russian Federation
A. L. Burmistrova
Chelyabinsk State University
Email: noemail@neicon.ru
Russian Federation
References
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- Hsiao E. Y., McBride S.W., Hsien S., Sharon G., Hyde E. R., et al. Microbiota modulate behavioral and physiological abnormalities associated with neurodevelopmental disorders. Cell 2013, 155 (7), 1451-1463.
- Bradley J. Ferguson, Sarah Marler, Lily L. Altstein, Evon Batey Lee, Micah O. Mazurek, et all. Associations between cytokines, endocrine stress response, and gastrointestinal symptoms in autism spectrum disorder. Brain Behav. Immun. 2016, 58, 57-62.
Supplementary files
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).