INTERLEUKINE EARLY RISK MARKERS OF ACUTE REJECTION IN KIDNEY TRANSPLANTATION

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Abstract

This article discusses the possibility of predicting post-transplant complications. The aim of our work is to evaluate the association of pre-operative level 21 of the cytokine in the blood plasma and during the post-transplant period. The analysis was first the differences in the initial level of biomarkers in patients without complications and with complications after transplantation. Our results confirmed that the screening of cytokines prior to transplantation may be used to predict the subsequent development of complications.

About the authors

T. V. Fedorenko

Kuban state medical University

Author for correspondence.
Email: noemail@neicon.ru
Russian Federation

N. V. Kolesnikova

Kuban state medical University

Email: noemail@neicon.ru
Russian Federation

E. F. Filippov

Kuban state medical University

Email: noemail@neicon.ru
Russian Federation

References

  1. Bertani A. Overcoming primary graft dysfunction after lung transplantation: are we finding our way there? / Bertani A. // Transplantation.- 2014.-№ 97.- Р. 1100-1101.
  2. Taniguchi M. Higher risk of kidney graft failure in the presence of anti-angiotensin II type-1 receptor antibodies/ Taniguchi M., Rebellato L. M., Cai J., Hopfield J., Briley K. P., Haisch C. E., Catrou P. G., Bolin P., Parker K., Kendrick W. T., et al. // Am J Transplant.- 2013.- № 13.- Р. 2577-2589.
  3. Porcheray F. Polyreactive antibodies developing amidst humoral rejection of human kidney grafts bind apoptotic cells and activate complement./ Porcheray F., Fraser J. W., Gao B., McColl A., DeVito J., Dargon I., Helou Y., Wong W., Girouard T. C., Saidman S. L., et al.// Am J Transplant.- 2013.-№ 13.- Р. 2590-2600.
  4. Li X. C. The significance of non-T-cell pathways in graft rejection: Implications for transplant tolerance / Transplantation.- 2010.- Vol. 90.- Р.1043-1047.
  5. Carvalho-Gaspar M. Chemokine gene expression during allograft rejection: Comparison of two quantitative PCR techniques / M. Carvalho-Gas-par, J. S. Billing, B. M. Spriewald, et al. // JImmunol Methods.- 2005.- Vol. 301.- Р.41-52.

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Copyright (c) 2017 Fedorenko T.V., Kolesnikova N.V., Filippov E.F.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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