Email this article Immune biomarkers of in-stent restenosis after percutaneous coronary interventions in myocardial infarction and stable angina patients
- Authors: Grachev N..1, Semenikhin A..1, Turmova E..1, Rublev V..2, Nazarenko S..2, Anohina N..2
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Affiliations:
- Pacific State Medical University
- Primorye Regional Clinical Hospital № 1
- Issue: Vol 21, No 3 (2018)
- Pages: 255-260
- Section: ORIGINAL ARTICLES
- URL: https://rusimmun.ru/jour/article/view/875
- DOI: https://doi.org/10.31857/S102872210002391-5
- ID: 875
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Abstract
The study was aimed to assess the prognostic role of infl ammation biomarkers to evaluate the risk for restenosis in myocardial infarction and stable angina patients undergoing percutaneous coronary intervention. The blood samples were tested immediately before and 7 days after percutaneous coronary intervention for IFN-γ, IL-6, IL-8, IL-17, TNF-α, TNF-β, TGF-β1 and TGF-β2. The key predictors of restenosis after percutaneous coronary intervention during one year were abnormal rates of IFN-γ pre-PCI (OR=5,21) and 7 days after (OR=3,84), IL-6 pre-PCI (OR=1,59), IL-8 pre-PCI (OR=1,73), IL-17 pre- PCI (OR=3,07) and 7 days after (OR=2,34), TNF-α pre-PCI (OR=1,88), TNF-β pre-PCI (OR=1,98) and growth factors: TGF-β1 7 days after PCI (OR=1,82) and TGF-β2 7 days after PCI (OR=2,04).
About the authors
N. . Grachev
Pacific State Medical University
Author for correspondence.
Email: noemail@neicon.ru
Russian Federation
A. . Semenikhin
Pacific State Medical University
Email: noemail@neicon.ru
Russian Federation
E. . Turmova
Pacific State Medical University
Email: noemail@neicon.ru
Russian Federation
V. . Rublev
Primorye Regional Clinical Hospital № 1
Email: noemail@neicon.ru
Russian Federation
S. . Nazarenko
Primorye Regional Clinical Hospital № 1
Email: noemail@neicon.ru
Russian Federation
N. . Anohina
Primorye Regional Clinical Hospital № 1
Email: noemail@neicon.ru
Russian Federation
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